Figure 7. Proposed Model for the Movement of EF-G Domain IV in Ribosome Recycling.
(A) Crystal structure of eEF2·Sordarin (dark blue), aligned with respect to domains I-II of E. coli EF-G, and superimposed with the structure of 70S-bound RRF (red). (B) Structures of EF-G (cyan) and RRF (green) in the 50S·EF-G·GDPNP·RRF complex. (C) Structure of EF-G (pale green) in the 50S·EF-G·GDP·Fusidic-acid complex, superimposed with the structure of 50S-bound RRF (green). (D) Superimposition of all above structures. See text for details.