Table 2.
Leptomycin B-induced p53 nuclear localization in ALTR cells
| Cell line | Leptomycin B (24 h, 4 μl/ml) |
|---|---|
| A1–5 | 93% (++++)a |
| ALTR1 | 37% (++) |
| ALTR3 | 8.8% |
| ALTR4 | 59% (++) |
| ALTR7 | 38.5% (++) |
| ALTR8 | 70% (+++) |
| ALTR11 | ND |
| ALTR12 | ND |
| ALTR14 | 54% (++) |
| ALTR15 | ND |
| ALTR16 | ND |
| ALTR19 | ND |
| ALTR23 | ND |
| ALTR25 | 50% (++) |
| ALTR26 | 23% (+) |
Abbreviations: ALTR, A1–5 Low Temperature Resistant; ND, not detectable nuclear localization.
a
Values indicate the % of cells with nuclear p53 after leptomycin B treatment. Qualitative ranking is given in parentheses.