Table 2.
Human ANTP-class homeobox genes and pseudogenes | |||||
HOXL subclass | |||||
Family | Gene symbol | Gene name | Location | Entrez gene ID | Previous symbols |
Cdx | CDX1 | caudal type homeobox 1 | 5q32 | 1044 | |
CDX2 | caudal type homeobox 2 | 13q12.2 | 1045 | CDX3 | |
CDX4 | caudal type homeobox 4 | Xq13.2 | 1046 | ||
Evx | EVX1 | even-skipped homeobox 1 | 7p15.2 | 2128 | |
EVX2 | even-skipped homeobox 2 | 2q31.1 | 344191 | ||
Gbx | GBX1 | gastrulation brain homeobox 1 | 7q36.1 | 2636 | |
GBX2 | gastrulation brain homeobox 2 | 2q37.2 | 2637 | ||
Gsx | GSX1 | GS homeobox 1 | 13q12.2 | 219409 | GSH1 |
GSX2 | GS homeobox 2 | 4q12 | 170825 | GSH2 | |
Hox1 | HOXA1 | homeobox A1 | 7p15.2 | 3198 | HOX1F |
HOXB1 | homeobox B1 | 17q21.32 | 3211 | HOX2I | |
HOXD1 | homeobox D1 | 2q31.1 | 3231 | HOX4G | |
Hox2 | HOXA2 | homeobox A2 | 7p15.2 | 3199 | HOX1K |
HOXB2 | homeobox B2 | 17q21.32 | 3212 | HOX2H | |
Hox3 | HOXA3 | homeobox A3 | 7p15.2 | 3200 | HOX1E |
HOXB3 | homeobox B3 | 17q21.32 | 3213 | HOX2G | |
HOXD3 | homeobox D3 | 2q31.1 | 3232 | HOX4A | |
Hox4 | HOXA4 | homeobox A4 | 7p15.2 | 3201 | HOX1D |
HOXB4 | homeobox B4 | 17q21.32 | 3214 | HOX2F | |
HOXC4 | homeobox C4 | 12q13.13 | 3221 | HOX3E | |
HOXD4 | homeobox D4 | 2q31.1 | 3233 | HOX4B | |
Hox5 | HOXA5 | homeobox A5 | 7p15.2 | 3202 | HOX1C |
HOXB5 | homeobox B5 | 17q21.32 | 3215 | HOX2A | |
HOXC5 | homeobox C5 | 12q13.13 | 3222 | HOX3D | |
Hox6-8 | HOXA6 | homeobox A6 | 7p15.2 | 3203 | HOX1B |
HOXB6 | homeobox B6 | 17q21.32 | 3216 | HOX2B | |
HOXC6 | homeobox C6 | 12q13.13 | 3223 | HOX3C | |
HOXA7 | homeobox A7 | 7p15.2 | 3204 | HOX1A | |
HOXB7 | homeobox B7 | 17q21.32 | 3217 | HOX2C | |
HOXB8 | homeobox B8 | 17q21.32 | 3218 | HOX2D | |
HOXC8 | homeobox C8 | 12q13.13 | 3224 | HOX3A | |
HOXD8 | homeobox D8 | 2q31.1 | 3234 | HOX4E | |
Hox9-13 | HOXA9 | homeobox A9 | 7p15.2 | 3205 | HOX1G |
HOXB9 | homeobox B9 | 17q21.32 | 3219 | HOX2E | |
HOXC9 | homeobox C9 | 12q13.13 | 3225 | HOX3B | |
HOXD9 | homeobox D9 | 2q31.1 | 3235 | HOX4C | |
HOXA10 | homeobox A10 | 7p15.2 | 3206 | HOX1H | |
HOXC10 | homeobox C10 | 12q13.13 | 3226 | HOX3I | |
HOXD10 | homeobox D10 | 2q31.1 | 3236 | HOX4D, HOX4E | |
HOXA11 | homeobox A11 | 7p15.2 | 3207 | HOX1I | |
HOXC11 | homeobox C11 | 12q13.13 | 3227 | HOX3H | |
HOXD11 | homeobox D11 | 2q31.1 | 3237 | HOX4F | |
HOXC12 | homeobox C12 | 12q13.13 | 3228 | HOX3F | |
HOXA13 | homeobox A13 | 7p15.2 | 3209 | HOX1J | |
HOXB13 | homeobox B13 | 17q21.32 | 10481 | ||
HOXC13 | homeobox C13 | 12q13.13 | 3229 | HOX3G | |
HOXD13 | homeobox D13 | 2q31.1 | 3239 | HOX4I | |
Mnx | MNX1 | motor neuron and pancreas homeobox 1 | 7q36.3 | 3110 | HLXB9, HB9, HOXHB9 |
Meox | MEOX1 | mesenchyme homeobox 1 | 17q21.31 | 4222 | MOX1 |
MEOX2 | mesenchyme homeobox 2 | 7p21.1 | 4223 | MOX2, GAX | |
Pdx | PDX1 | pancreatic and duodenal homeobox 1 | 13q12.2 | 3651 | IPF1, IUF1, IDX1, STF1 |
NKL subclass | |||||
Barhl | BARHL1 | BarH-like homeobox 1 | 9q34.13 | 56751 | |
BARHL2 | BarH-like homeobox 2 | 1p22.2 | 343472 | ||
Barx | BARX1 | BARX homeobox 1 | 9q22.32 | 56033 | |
BARX2 | BARX homeobox 2 | 11q24.3 | 8538 | ||
Bsx | BSX | brain specific homeobox | 11q24.1 | 390259 | |
Dbx | DBX1 | developing brain homeobox 1 | 11p15.1 | 120237 | |
DBX2 | developing brain homeobox 2 | 12q12 | 440097 | ||
Dlx | DLX1 | distal-less homeobox 1 | 2q31.1 | 1745 | |
DLX2 | distal-less homeobox 2 | 2q31.1 | 1746 | TES1 | |
DLX3 | distal-less homeobox 3 | 17q21.33 | 1747 | ||
DLX4 | distal-less homeobox 4 | 17q21.33 | 1748 | DLX7, DLX8, DLX9, BP1 | |
DLX5 | distal-less homeobox 5 | 7q21.3 | 1749 | ||
DLX6 | distal-less homeobox 6 | 7q21.3 | 1750 | ||
Emx | EMX1 | empty spiracles homeobox 1 | 2p13.2 | 2016 | |
EMX2 | empty spiracles homeobox 2 | 10q26.11 | 2018 | ||
En | EN1 | engrailed homeobox 1 | 2q14.2 | 2019 | |
EN2 | engrailed homeobox 2 | 7q36.3 | 2020 | ||
Hhex | HHEX | hematopoietically expressed homeobox | 10q23.33 | 3087 | HEX, PRH, PRHX |
Hlx | HLX | H2.0-like homeobox | 1q41 | 3142 | HLX1, HB24 |
Lbx | LBX1 | ladybird homeobox 1 | 10q24.32 | 10660 | LBX1H, HPX6 |
LBX2 | ladybird homeobox 2 | 2p13.1 | 85474 | ||
Msx | MSX1 | msh homeobox 1 | 4p16.2 | 4487 | HOX7 |
MSX2 | msh homeobox 2 | 5q35.2 | 4488 | HOX8, MSH | |
MSX2P1 | msh homeobox 2 pseudogene | 17q23.2 | 55545 | HPX5, MSX2P | |
Nanog | NANOG | Nanog homeobox | 12p13.31 | 79923 | |
NANOGP1 | Nanog homeobox pseudogene 1 | 12p13.31 | 404635 | NANOG2 | |
NANOGP2 | Nanog homeobox pseudogene 2 | 2q36.1 | 414131 | NANOGP4 | |
NANOGP3 | Nanog homeobox pseudogene 3 | 6p12.1 | 340217 | ||
NANOGP4 | Nanog homeobox pseudogene 4 | 7p15.1 | 414132 | NANOGP2 | |
NANOGP5 | Nanog homeobox pseudogene 5 | 9q31.1 | 414133 | ||
NANOGP6 | Nanog homeobox pseudogene 6 | 10q24.2 | 414134 | ||
NANOGP7 | Nanog homeobox pseudogene 7 | 14q32.12 | 414130 | NANOGP3 | |
NANOGP8 | Nanog homeobox pseudogene 8 | 15q14 | 388112 | NANOGP1 | |
NANOGP9 | Nanog homeobox pseudogene 9 | Xq12 | 349386 | NANOGP6 | |
NANOGP10 | Nanog homeobox pseudogene 10 | Xp11.3 | 349372 | NANOGP5 | |
NANOGP11 | Nanog homeobox pseudogene 11 | 6q25.2 | 414135 | ||
Nk1 | NKX1-1 | NK1 homeobox 1 | 4p16.3 | 54279 | NKX1.1, HSPX153, HPX153 |
NKX1-2 | NK1 homeobox 2 | 10q26.13 | 390010 | NKX1.2, C10orf121 | |
Nk2.1 | NKX2-1 | NK2 homeobox 1 | 14q13.3 | 7080 | NKX2.1, NKX2A, TTF1, TITF1 |
NKX2-4 | NK2 homeobox 4 | 20p11.22 | 4823 | NKX2.4, NKX2D | |
Nk2.2 | NKX2-2 | NK2 homeobox 2 | 20p11.22 | 4821 | NKX2.2, NKX2B |
NKX2-8 | NK2 homeobox 8 | 14q13.3 | 26257 | NKX2.8, NKX2H | |
Nk3 | NKX3-1 | NK3 homeobox 1 | 8p21.2 | 4824 | NKX3.1, NKX3A |
NKX3-2 | NK3 homeobox 2 | 4p15.33 | 579 | NKX3.2, NKX3B, BAPX1 | |
Nk4 | NKX2-3 | NK2 homeobox 3 | 10q24.2 | 159296 | NKX2.3, NKX2C, NKX4-3, CSX3 |
NKX2-5 | NK2 homeobox 5 | 5q35.1 | 1482 | NKX2.5, NKX2E, NKX4-1, CSX, CSX1 | |
NKX2-6 | NK2 homeobox 6 | 8p21.2 | 137814 | NKX2.6, NKX4-2, CSX2 | |
Nk5/Hmx | HMX1 | H6 family homeobox 1 | 4p16.1 | 3166 | NKX5-3, H6 |
HMX2 | H6 family homeobox 2 | 10q26.13 | 3167 | NKX5-2, H6L | |
HMX3 | H6 family homeobox 3 | 10q26.13 | 340784 | NKX5-1 | |
Nk6 | NKX6-1 | NK6 homeobox 1 | 4q21.23 | 4825 | NKX6.1, NKX6A |
NKX6-2 | NK6 homeobox 2 | 10q26.3 | 84504 | NKX6.2, NKX6B, GTX | |
NKX6-3 | NK6 homeobox 3 | 8p11.21 | 157848 | NKX6.3 | |
Noto | NOTO | notochord homeobox | 2p13.2 | 344022 | |
Tlx | TLX1 | T-cell leukemia homeobox 1 | 10q24.32 | 3195 | HOX11, TCL3 |
TLX2 | T-cell leukemia homeobox 2 | 2p13.1 | 3196 | HOX11L1, NCX | |
TLX3 | T-cell leukemia homeobox 3 | 5q35.1 | 30012 | HOX11L2, RNX | |
Vax | VAX1 | ventral anterior homeobox 1 | 10q26.11 | 11023 | |
VAX2 | ventral anterior homeobox 2 | 2p13.3 | 25806 | ||
Ventx | VENTX | VENT homeobox | 10q26.3 | 27287 | VENTX2, HPX42B |
VENTXP1 | VENT homeobox pseudogene 1 | Xp21.3 | 139538 | VENTX2P1, NA88A | |
VENTXP2 | VENT homeobox pseudogene 2 | 13q31.1 | 347975 | VENTX2P2 | |
VENTXP3 | VENT homeobox pseudogene 3 | 12q21.1 | 349814 | VENTX2P3 | |
VENTXP4 | VENT homeobox pseudogene 4 | 3p24.2 | 152101 | VENTX2P4 | |
VENTXP5 | VENT homeobox pseudogene 5 | 8p12 | 442384 | ||
VENTXP6 | VENT homeobox pseudogene 6 | 8q21.11 | 552879 | ||
VENTXP7 | VENT homeobox pseudogene 7 | 3p24.3 | 391518 | VENTX1, HPX42 |
Human ANTP class homeobox genes and pseudogenes including full names, chromosomal locations, Entrez Gene IDs and previous symbols. NANOGP1 is a duplicate of NANOG.