Table V.
Mortality According to MBL Deficiency Genotype during 8 yr Follow-up
| Noncarriers
|
Heterozygotes
|
Homozygotes
|
||||||
|---|---|---|---|---|---|---|---|---|
| IncidenceN/10,000person · yr | RRa | IncidenceN/10,000person · yr | P-valueb | RRa (95% CI) | IncidenceN/10,000 person · yr |
P-valueb | RRa(95% CI) | |
| Death from any cause | 235 | 1.0 | 244 | 0.44 | 1.0 (0.95–1.2) | 274 | 0.12 | 1.1 (0.87–1.3) |
| Infectious and parasitic diseases | 1.9 | 1.0 | 2.7 | 0.53 | 1.5 (0.52–4.2) | 2.6 | 0.78 | 1.4 (0.17–13) |
| Respiratory infections | 4.3 | 1.0 | 2.7 | 0.40 | 0.66 (0.28–1.6) | 2.6 | 0.61 | 0.44 (0.05–3.6) |
| Respiratory disorders | 14 | 1.0 | 10 | 0.14 | 0.73 (0.45–1.2) | 18 | 0.56 | 1.2 (0.54–2.7) |
| Cardiovascular disorders | 41 | 1.0 | 31 | 0.04 | 0.73 (0.55–0.95) | 49 | 0.44 | 1.1 (0.70–1.8) |
| Malignant neoplasms | 58 | 1.0 | 63 | 0.45 | 1.1 (0.90–1.3) | 78 | 0.13 | 1.3 (0.87–1.9) |
| Digestive disorders | 7.0 | 1.0 | 5.3 | 0.41 | 0.82 (0.42–1.6) | 5.2 | 0.69 | 0.66 (0.15–2.8) |
| Musculoskeletal disorders | 1.4 | 1.0 | 0 | — | — | 0 | — | — |
| Neuropsychiatric disorders | 3.4 | 1.0 | 3.4 | 0.96 | 1.4 (0.56–3.3) | 0 | — | — |
a
Relative risks (RR) were adjusted for age, gender, smoking habits, systolic blood pressure, alcohol, cholesterol, body mass index, and physical inactivity.
b
P-values by log-rank test. Infectious and parasitic diseases: 001–136, 320, 323, 612–614, 620, 622, A00–B99, G00, G03–G04, N70–N73; respiratory infections: 460–486, 381–382, J00–J22, H65–H66; respiratory disorders: 490–519, J30–J99; cardiovascular disorders: 390–458, I00–I99; malignant neoplasms: 140–209, C00–C97; digestive disorders: 530–577, K20–K99; musculoskeletal disorders: 710–738, M00–M99; neuropsychiatric disorders: 290–315, 321–322, 324–358, F01–F99, G06–G98.