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. 2004 Oct 18;200(8):957–965. doi: 10.1084/jem.20041214

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Copyright © 2004, The Rockefeller University Press

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Figure 2. — (A) The addition of each activating receptor is associated with a 1.2-fold reduction in prevalence. A linear logistic model was used to relate the prevalence of preeclampsia to the numbers of activating receptors possessed by the mother (KIR2DS1, 2DS2, 2DS3, 2DS4wt, and 2DS5). Control pregnancies were compared with affected mothers presented with fetal C2 as before. The model suggests an approximate 1.2-fold reduction in prevalence with each additional activating receptor. The sample size for the mothers with five activating receptors was very small (n = 6 for control and preeclampsia mothers combined). (B) A multiplicative model is a good fit to the data. A plot of the expected versus observed numbers of affected mothers with increasing numbers of activating receptors shows that the logistic model provides a good fit.