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. 2004 Oct 18;200(8):957–965. doi: 10.1084/jem.20041214

Table II.

KIR Gene/Genotype Frequencies in Control and Preeclampsia Mothers and Those Preeclampsia Mothers Presented with Fetal C2 in Homozygous (2 + 2) or Heterozygous (1 + 2) Form

Gene/genotype Control mothers Preeclampsia mothers Preeclampsia subsets with fetal C2 (a, b, d, f, g)a
% (n = 201) % (n = 200) % (n = 109)
2DL2 53 (107) 52 (103) 40b (44)
P = 0.033
2DS1 47 (94) 38 (76) 34b (37)
P = 0.031
2DS2 53 (108) 52 (104) 42 (46)
P = 0.058
2DS3 29 (58) 24 (47) 15b (16)
P = 0.005
2DS5 39 (83) 32 (83) 33 (36)
P = 0.179
2DL5 58 (116) 47b (94)
P = 0.036
41b (45)
P = 0.006
Genotype AA 25 (50) 35b (69)
P = 0.038
44b(48)
P = 0.001

The B haplotypes KIR, 2DL2, 2DL5, 2DS1, 2DS3, and 2DS5 all occur at lower frequency in the preeclampsia mothers presented with HLA-C2 as compared with the controls.

a

The letters a, b, d, f, and g refer to the subsets in Table III and Fig. 1 B.

b

Significantly different frequencies between preeclampsia and control mothers.