Table II.
Gene/genotype | Control mothers | Preeclampsia mothers | Preeclampsia subsets with fetal C2 (a, b, d, f, g)a |
---|---|---|---|
% (n = 201) | % (n = 200) | % (n = 109) | |
2DL2 | 53 (107) | 52 (103) | 40b (44) P = 0.033 |
2DS1 | 47 (94) | 38 (76) | 34b (37) P = 0.031 |
2DS2 | 53 (108) | 52 (104) | 42 (46) P = 0.058 |
2DS3 | 29 (58) | 24 (47) | 15b (16) P = 0.005 |
2DS5 | 39 (83) | 32 (83) | 33 (36) P = 0.179 |
2DL5 | 58 (116) | 47b (94) P = 0.036 |
41b (45) P = 0.006 |
Genotype AA | 25 (50) | 35b (69) P = 0.038 |
44b(48) P = 0.001 |
The B haplotypes KIR, 2DL2, 2DL5, 2DS1, 2DS3, and 2DS5 all occur at lower frequency in the preeclampsia mothers presented with HLA-C2 as compared with the controls.
Significantly different frequencies between preeclampsia and control mothers.