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. 2004 Nov 15;200(10):1289–1297. doi: 10.1084/jem.20041789

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Copyright © 2004, The Rockefeller University Press

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Figure 8. — Response of mice with complete or T cell–specific IL-10 deficiency to LPS. 20 μg of LPS/g body weight were injected i.p. (A) Survival of IL-10 ^FL/FL CD4-Cre⁺ mice (□, n = 10) and IL-10 ^FL/FL Cre⁻ control littermates (▪, n = 10), and IL-10 ^D/D animals (○, n = 10) and IL-10 ^D/WT control littermates (•, n = 10). (B) Additional animals were bled 6 h after LPS injection and serum TNF-α, IFN-γ, and IL-12 levels were determined (symbols as in A).