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. 2004 Aug 16;200(4):493–505. doi: 10.1084/jem.20040643

Figure 4.

Figure 4.

Distribution of SP thymocytes in the thymuses of sublethally irradiated adult CCR7- or CCR7L-deficient mice. (A and C) Three-color immunofluorescence analysis of the thymuses from nonirradiated (A) and 4 Gy–irradiated (C) mice. Dashed lines indicate junctions between the cortex and the medulla. C, cortex; M, medulla. Arrows in A indicate CD4+CD8 cells (in green) in the cortical region. (B) Flow cytometric analysis of thymocytes from nonirradiated and irradiated mice. Means ± SEs of total thymocytes are also indicated. (D) Means ± SEs of the numbers of CD4+CD8 (4SP) and CD4CD8+ (8SP) cells per unit area (0.01 mm2) of indicated regions of thymus sections are indicated. Cor, cortex; CMJ, cortico-medullary junction; Med, medulla.