Table I.
Properties of the island's ORFs
| Presence in meningococcal strains
|
|||||
|---|---|---|---|---|---|
| Gene | Protein length |
In 29 “invasive” |
In 20 “noninvasive |
Protein homologies (BlastP)a | Conserved domains (BlastP)b |
| ORF1, NMA1792 | 429 | 27 | 0 | ORF C7 [Ralstonia solanacearum plasmid] (NP_052309.1), 9 × 10-24; RstA1 protein [Vibrio cholerae prophage] (NP_231106.1), 1 × 10-11 |
replication initiation factor (pfam02486), 6 × 10-42; phage replication protein RstA (COG2946), 4 × 10-143 |
| ORF2, NMA1793 | 104 | 29 | 1 | NSc | NS |
| ORF3, NMA1794 | 67 | 29 | 1 | NS | NS |
| ORF4, NMA1795 | 77 | 29 | 1 | NS | NS |
| ORF5, NMA1796 | 102 | 29 | 1 | NS | NS |
| ORF6, NMA1797 | 547 | 29 | 2 | NS | Neisserial TspB proteins |
| ORF7, NMA1798 | 95 | 29 | 2 | NS | NS |
| ORF8, NMA1799 | 401 | 29 | 2 | ORF C6 [Ralstonia solanacearum plasmid] (NP_052316.1), 2 × 10-31; phage-related protein [Xylella fastidiosa] (NP_779131.1), 3 × 10-18 |
zonular occludens toxin (Zot) (pfam05707), 7 × 10-47; NS |
| ORF9, NMA1800 | 323 | 26 | 0 | transposase [Escherichia coli IS621] (BAC76887.1), 3 × 10-37 |
transposase (COG3547), 1 × 10-17 |
a
This column's data are organized as “protein [species] (identifier), significance.”
b
This column's data are organized as “family (identifier), significance.”
c
NS, no significant homologies were found.