Figure 4.
Lymphocyte rolling in PLNs is L-selectin–dependent. LNCs rolling fractions were analyzed before (control) and after treatment of cells and animals with blocking mAbs (α4, mAb PS/2; LFA-1, mAb Tib 213; L-selectin, mAb Mel-14). Bars depict rolling fractions as percentage of control cell rolling in the same venule; data shown are mean ± SEM of rolling fractions from 3–5 experiments of 4–10 vessels each. **P <0.001 versus all groups (Kruskal Wallis test with Bonferoni correction).