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. 1998 Jan 19;187(2):147–159. doi: 10.1084/jem.187.2.147

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Absence of germinal centers and dendritic cell networks in spleens of challenged p52/p100 (−/−) mice. 13–15-wk-old p52/p100 (−/−), (+/−), and (+/−) control mice were challenged by intraperitoneal injection of 100 μg of alum-adsorbed TNP-KLH. Frozen sections of spleens were obtained 8 or 17 d after injection and stained (A) with PNA, anti-CD35(CR1), or FDC-M1 antibodies and (B) with PNA ( purple) and anti-B220 antibodies ( pink), as indicated. Stained cryosections from representative pairs of littermates are shown.