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. 1998 Jan 19;187(2):265–270. doi: 10.1084/jem.187.2.265

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Cytotoxicity of NW38-IVS-1 against NY-ESO-1⁺ and NY-ESO-1⁻ cell lines. Specific lysis of the autologous NY-ESO-1⁺ melanoma cell line NW-MEL-38, and the NY-ESO-1⁺/HLA-A2⁺ allogeneic melanoma cell lines SK-MEL-37 and MZ-MEL-19 was observed. The NY-ESO-1⁺ MHC class I^- melanoma cell line SK-MEL-19, the NY-ESO-1⁻ HLA-A2⁺ melanoma cell line NW-MEL-145, K562, and NW38 PHA blasts used as controls were not lysed. Values represent the specific lysis of ⁵¹Cr-labeled target cells (E/T ratios: 90 [solid], 30 [checkered], 10 [striped], and 1:1 [open], as assessed by a standard ⁵¹Cr-release assay.