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. 1998 Feb 2;187(3):307–317. doi: 10.1084/jem.187.3.307

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Cytokine production in IL-4^−/− (solid columns) and IL-4^+/+ (dotted columns) mice infected with C. albicans. Total spleen cells (A) and purified CD4⁺ T splenocytes (B), obtained from uninfected mice (0) or 3 d after intravenous challenge with 5 × 10⁵ CA-6 cells, were mitogen or antigen stimulated in vitro, respectively, for 48 h. Cytokine levels were determined by means of cytokine-specific ELISA. *, Cytokine levels below the detection limit of the assay, as indicated on the y-axis.