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. 1998 Feb 16;187(4):655–660. doi: 10.1084/jem.187.4.655

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Functional responses of human blood leukocytes to BCA-1. (a) In vitro chemotaxis of human B lymphocytes (closed circles), T lymphocytes cultured for 19 d in the presence of 250 U/ml IL-2 (open circles), monocytes (open squares), and neutrophils (open triangles) in response to increasing concentrations of BCA-1. (b) [Ca²⁺]_i changes in human blood leukocytes. Fura-2–loaded cells were stimulated sequentially with 100 nM BCA-1 followed by another chemokine, and changes in [Ca²⁺]_i were recorded. The data are representative for four independent experiments.

Functional responses of human blood leukocytes to BCA-1. (a) In vitro chemotaxis of human B lymphocytes (closed circles), T lymphocytes cultured for 19 d in the presence of 250 U/ml IL-2 (open circles), monocytes (open squares), and neutrophils (open triangles) in response to increasing concentrations of BCA-1. (b) [Ca²⁺]_i changes in human blood leukocytes. Fura-2–loaded cells were stimulated sequentially with 100 nM BCA-1 followed by another chemokine, and changes in [Ca²⁺]_i were recorded. The data are representative for four independent experiments.