Table 2.
Genotypic Analysis of the Number of CAAT Repeats (n) in licA in Nontypable H. influenzae (NTHI) in Human Respiratory Tract Secretions*
Genotype (n =) | NTHI pneumonia‡ | Predicted phenotype ChoP+/ChoP− | Corresponding initiation codon(s) | |||
---|---|---|---|---|---|---|
6 | no | + | γ | |||
24 | no | + | γ | |||
24 | no | + | γ | |||
24 | no | + | γ | |||
18 | no | + | γ | |||
25 | yes | + | α/β | |||
30 | yes | + | γ | |||
33 | no | + | γ | |||
20 | yes | − | none | |||
18 | yes | + | γ | |||
21 | yes | + | γ | |||
18 | no | + | γ | |||
18 | no | + | γ | |||
18 | no | + | γ |
The relationship between genotype, predicted phenotype, and the designation of corresponding initiation codons is described in Fig. 6.
Clinical criteria for NTHI pneumonia are described in methods section.