Figure 1.
Serum levels of IL-6 in DBA/1J mice with CIA correlated with the arthritis index. Type II collagen immunized mice were bled 6 wk after CII immunization. IL-6 activity was measured by hybridoma growth assay and the arthritis index evaluated as described in Materials and Methods. Results were analyzed using the Spearman correlation coefficient. Rs = 0.694; P = 0.008.