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. 1998 Feb 16;187(4):461–468. doi: 10.1084/jem.187.4.461

Figure 2.

Figure 2

Effects of antibody treatment on arthritis index of CII-immunized DBA/1J mice. (A) Mice (n = 9 for each group) were treated once per week with 1 mg/mouse (white symbols) or 0.5 mg/mouse (black symbols) of either anti–IL-6Rα antibody 15A7 (circles), anti–dinitrophenyl hapten antibody LO-DNP (triangles), or left untreated (squares). *P <0.05 either 15A7 or LO-DNP versus none. (B) Mice were treated with 1 mg/ wk/mouse of either anti–IL6-Rα antibody 15A7 (circles; n = 9), rat total IgG antibodies (diamonds; n = 8), or left untreated (squares; n = 8). *P < 0.02 15A7 versus none; # P <0.04 total IgG versus none. Results were reported as mean ± SD. The weeks after the first immunization with CII and the duration of antibody treatment are indicated on the abscissa.

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