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. 1998 Apr 6;187(7):985–996. doi: 10.1084/jem.187.7.985

Figure 8.

Figure 8

Basal and specific Ig production in vivo. (A) Ig isotype concentrations. The concentration of serum Ig in unimmunized control (closed circles), heterozygotes (closed triangles), and p105−/− (open circles) mice was determined by isotype-specific ELISA. (B) T cell–dependent antibody production. Mice were immunized with NP-KLH and the levels of NP-specific IgG1 were determined 1, 2, and 3 wk after immunization. (C) T cell–independent antibody production. Mice were immunized with NP-LPS and the levels of NP-specific IgG3 were determined 1, 2, and 3 wk after immunization. Each symbol represents the value obtained from one animal. Horizontal bars, mean values.