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. 1998 Apr 6;187(7):1029–1035. doi: 10.1084/jem.187.7.1029

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Protein C activation by cultured endothelial cells. Protein C was incubated with venous (A and B) or arterial (C and D) endothelial cells in the presence of thrombin, and generated APC was measured. The y-axis represents velocity of APC generation (pM/min) in the presence of indicated concentrations of protein C (A and C). The V_max and K _d values were calculated by the Eadie-Hostee plot (B and D).