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. 1998 Apr 20;187(8):1215–1224. doi: 10.1084/jem.187.8.1215

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Intracellular localization of downmodulated CCR5. CHO/CCR5 were treated with medium (a and d), medium with RANTES (250 nM; b and e), or AOP-RANTES (125 nM; c and f ) for 1 h at 37°C. After fixation and permeabilization, the cells were costained for CCR5 (green) and TfR (a, b, and c; red) or a lysosomal marker Lgp-B (d, e, and f; red). Scale bar, 40 mm.