Figure 2.
Sensitizing effect of peptide caspase inhibitors on TNF-induced necrosis in L929 cells, added 2 h before TNF treatment. (A) Without addition of BHA. •, Ac-YVAD-cmk (100 μM); ○, zDEVD-fmk (100 μM); ▾, Ac-YVAD-cmk + zDEVD-fmk (100 μM each); ▿, zVAD-fmk (25 μM); ▪, zD-fmk (25 μM); □, zAAD-cmk (100 μM); and ♦, control. (B) With BHA (100 μM) added at the same time as TNF (same symbols as in A).