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. Author manuscript; available in PMC: 2008 Jan 23.
Published in final edited form as: Biochemistry. 2007 Dec 15;47(1):398–404. doi: 10.1021/bi702004b

Figure 3. FRET to measure the extent of cleft closure with various agonists.

Figure 3

Extent of activation (normalized to glutamate activation) versus distances between residues 394 and 652 in S1S2-T394C-S652C as determined from the fluorescence lifetimes for the series of willardiines and agonists glutamate, AMPA, and kainate (9).