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. 1998 Jun 1;187(11):1789–1797. doi: 10.1084/jem.187.11.1789

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Absence of follicular localization of immune complexes in C1qA ^−/− mice. Spleens from wild-type (129/Sv × C57BL/6; n = 5) and strain-matched C1qA ^−/− (n = 5) mice were taken 24 h after intravenous injection with 500 μg FITC-labeled HAGG. FITC localization (green) was assessed in splenic sections relative to germinal centers (PNA expression; red) in wild-type (A) and C1qA ^−/− (B) mice. FDCs were detected by mAb FDC-M1 (red) in wild-type (C) and C1qA ^−/− (D) mice. Original magnification: 20 (A, B, and D) and 40 (C).