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. 1998 Dec 21;188(12):2369–2374. doi: 10.1084/jem.188.12.2369

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In vivo analysis of IgG1 production in heterozygous targeted F₁ and wild-type control mice. Immunoglobulin levels of IgG1^a and of total IgG1 (IgG1^a and IgG1^b) were determined in sera of 8–12-wk-old mice by ELISA. The detection limit was 0.2 μg/ml.