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. 1998 Dec 21;188(12):2321–2333. doi: 10.1084/jem.188.12.2321

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Rescue of CD4 lineage–committed cells in OVA TCR tg, but not HY TCR tg, mice upon forced expression of CD8. Thymocytes and lymph node cells from HY TCR, HY TCR/CD8ααβ, OVA TCR, and OVA TCR/CD8ααβ tg mice were analyzed by three-color flow cytometry using the antibodies anti-CD4, anti-CD8, T3.70 (for the HY TCR), and anti-Vα2 (for the OVA TCR). The CD4/CD8 profiles are gated on the transgenic TCR^hi cells. The percentages are indicated for CD4-expressing cells within the clonotype^hi population.