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. 1998 Dec 21;188(12):2225–2231. doi: 10.1084/jem.188.12.2225

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HECA-452 reactivity of CD4⁺ T cells in response to varying culture conditions. HECA-452 staining of FucT-VII reporter epitopes (5) was used to assess FucT-VII activity. Naive CD4⁺ T cells (A) or unfractionated CD4⁺ T cells (B–D) were activated with either anti-CD3/anti-CD28 (A and B), PHA-P (C), or TSST-1 (D). In all panels, squares denote cultures containing IL-2 alone, diamonds denote cultures containing IL-2 + IL-4, and circles denote cultures containing IL-2 + IL-12. Data are presented as percent HECA-452 positive lymphocytes for each culture condition at the indicated time point.