Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1998 Jul 20;188(2):233–245. doi: 10.1084/jem.188.2.233

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Baseline ASC frequencies and spontaneous IgG secretion in cohort 1. ASC frequencies were determined in freshly isolated PBMCs from uninfected individuals (n = 6) and from three groups of individuals who had been infected with HIV-1 for varying lengths of time. All study subjects were drug naive at the time of assay except for one individual whose baseline value could only be determined after 1 wk of therapy (indicated by asterisk). ELISPOT plates were coated with either (a) anti–human IgG Fc to detect IgG-ASCs or (b) anti–human IgM Fc to detect IgM-ASCs. (c) Spontaneous IgG secretion after 8 d of culture was also measured by ELISA for the same individuals. Bars represent the median values for each group.