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Structure of S. aureus PepG. The shaded area on the PepG monomer shows the minimal component that accounts for the ability of PepG to synergize with LTA (or IFN-γ) to induce NO formation in J774.2 macrophages. The points at which enzymes lyse PepG are identified by markers ( filled circle, mutanolysin or M1; open square, lysostaphin; filled triangle, SALE). Numbers, Amino acid position on the stem peptide.
