Table 1.
Effect of LTA and PepG from S. aureus or B. subtilis on Nitrite Formation in Macrophages
| Component | Nitrite formation at concentration (μg/ml) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0.01 | 0.1 | 1 | 10 | 30 | ||||||
| μM | μM | μM | μM | μM | ||||||
| S. aureus LTA | 1.8 ± 0.2 | 14.0 ± 2.3* | 39.9 ± 1.2* | 51.6 ± 1.2* | 56.8 ± 1.7* | |||||
| S. aureus PepG | 1.4 ± 0.2 | 2.0 ± 0.1 | 2.1 ± 0.3 | 2.9 ± 0.4 | 3.3 ± 0.8 | |||||
| B. subtilis LTA | 1.9 ± 0.1 | 1.7 ± 0.1 | 2.1 ± 0.2 | 2.4 ± 0.2 | 5.7 ± 1.1 | |||||
| B. subtilis PepG | 2.0 ± 0.1 | 1.5 ± 0.1 | 2.1 ± 0.2 | 6.6 ± 0.2 | 17.0 ± 0.9* | |||||
Data are given as mean ± SE of 12 wells from four independent experiments.
*
P <0.05 compared with untreated cells (Dunnett's test).