Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1998 Jul 20;188(2):351–364. doi: 10.1084/jem.188.2.351

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Effects of protonophores and V-ATPase inhibitors on pH_p. pH_p was measured by ratio imaging as described for Fig. 1 (see Materials and Methods) in peritoneal macrophages obtained from wild-type mice (open symbols) and Nramp1 ^−/− mice (filled symbols). Phagosome formation was induced using live, fluoresceinated M. bovis. After acquiring baseline measurements, 10 μM CCCP (A) or 100 nM concanamycin (B, CCM) was added to both samples. Data are representative of five determinations.

Effects of protonophores and V-ATPase inhibitors on pH_p. pH_p was measured by ratio imaging as described for Fig. 1 (see Materials and Methods) in peritoneal macrophages obtained from wild-type mice (open symbols) and Nramp1 ^−/− mice (filled symbols). Phagosome formation was induced using live, fluoresceinated M. bovis. After acquiring baseline measurements, 10 μM CCCP (A) or 100 nM concanamycin (B, CCM) was added to both samples. Data are representative of five determinations.