Figure 7.
Amino acid sequence of TRIM. The putative transmembrane region is boxed. The tyrosine-based signaling motifs are depicted underneath the corresponding sequence; the peptide sequences obtained by nanoelectrospray tandem mass spectrometry of purified pp29/30 are double-underlined. Tyrosine residues are underlined. Note that TRIM does not possess a leader sequence, and that a cysteine residue is present in the extracellular domain (C7). The sequence data are available from EMBL/GenBank under accession no. AJ224878.