Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1998 Aug 3;188(3):431–438. doi: 10.1084/jem.188.3.431

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

C5b-9 generated by Aβ 1–42-mediated complement activation is functionally active. (a) NT2 cells were incubated with preaggregated Aβ 1–42 at the designated concentrations in NHS, or in NHS containing 10 mM EDTA; serum only lacks Aβ. Flow cytometric analyses with a rabbit Ab to C5b-9 neoantigens are shown. Numbers (right), Percentage of C5b-9⁺ cells, as determined by their relationship to the marker (arrow, dashed line). (b) Density plot analyses of propidium iodide and C5b-9 (FITC C5b-9) reactivities are shown. For clarity, only live cells are depicted.

C5b-9 generated by Aβ 1–42-mediated complement activation is functionally active. (a) NT2 cells were incubated with preaggregated Aβ 1–42 at the designated concentrations in NHS, or in NHS containing 10 mM EDTA; serum only lacks Aβ. Flow cytometric analyses with a rabbit Ab to C5b-9 neoantigens are shown. Numbers (right), Percentage of C5b-9⁺ cells, as determined by their relationship to the marker (arrow, dashed line). (b) Density plot analyses of propidium iodide and C5b-9 (FITC C5b-9) reactivities are shown. For clarity, only live cells are depicted.