Figure 4.

Time kinetics of ERK2, JNK, and p38 responses upon BCR engagement. After BCR stimulation, DT40 cell lysates were immunoprecipitated with anti-ERK2 Ab, anti-JNK1 Ab, or anti-p38 Ab. The kinase activities were assayed using GST–Elk1, GST–c-Jun, and GST–ATF2 as substrates for ERK2, JNK, and p38, respectively.