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. 1998 Oct 5;188(7):1231–1238. doi: 10.1084/jem.188.7.1231

Figure 3.

Figure 3

Sequence analysis of VκJκ- intron-RS rearrangements from IgMλ hybridomas. (A) Sequences of the VκJκ rearrangements. The first digit in the hybridoma name indicates the fusion experiment number. Myeloma fusion partners were either NSO-bcl2 (fusion 1) or SP2/0 (fusions 2–5). Vκ gene family and Jκ gene usage were assigned as described in Fig. 2. P and NP denote productive and nonproductive VκJκ rearrangements, respectively. Translated amino acid sequences of Vκ FWR, CDR, and Jκ sequences to the conserved phenylalanine (F) residue are shown for productive rearrangements, and Vκ FWR and CDR sequences, with * denoting an out of frame VκJκ join and # denoting an in-frame stop codon, are shown for nonproductive rearrangements. These sequence data are available from EMBL/Genbank/DDBJ under accession numbers AF087023–AF087034 and AF087460–AF087467. (B) Sequences of the RS rearrangements (as described in Fig. 2).