Table 1.

Disease Variables in Mice Given Higher Doses of NTS IgG

		1 mg				2 mg
		Tg + ve		Tg − ve		Tg + ve		Tg − ve
Albuminuria (μg/mg creatinine)		31,342 ± 6,631		28,361 ± 9,962		29,661 ± 10,296		23,667 ± 5,514
IF staining intensity for C3		0.3 ± 0.2*		1.8 ± 0.5*		0.3 ± 0.2*		1.4 ± 0.2*

Transgene positive and littermate negative mice were injected intravenously with 1 or 2 mg NTS IgG. Urine was collected for 18 h for albumin and creatinine determinations, after which animals were killed and renal tissue was processed to determine glomerular C3 binding by IF microscopy. Data represent the mean ± SEM.  

^*  P < 0.02 by ANOVA.