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. 1998 Sep 21;188(6):1159–1171. doi: 10.1084/jem.188.6.1159

Figure 3.

Figure 3

Figure 3

Relationship between viremia and CD4+ T lymphocyte counts for SHIV variants with different envelope glycoprotein domains. A “set-point” value for the absolute CD4+ T lymphocyte count in each animal (the median of the CD4 counts recorded on days 14–36 after infection) was plotted against the cumulative p27 antigenemia (area under the p27 versus time curves in Fig. 2 B). The data were grouped according to the sequences (either wild-type 89.6 or containing the KB9 passage- associated changes) of the viral envelope glycoprotein ectodomains (A) or cytoplasmic tails (B). The curves are fitted to the data using a nonlinear exponential decay model.