Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1998 Sep 21;188(6):1159–1171. doi: 10.1084/jem.188.6.1159

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Replication and syncytium-forming ability of SHIV variants. (A) Rhesus PBMCs were PHA-stimulated and infected with equal amounts of SHIV-89.6, SHIV-89.6*, SHIV-KB9ct, SHIV-KB9ecto, and SHIV-KB9. Cells were maintained in the presence of IL-2 for the duration of the experiment and an aliquot of the culture medium was removed every day for RT analysis. (B) Uninfected CEM×174 cultures (mock) were compared with cultures infected with SHIV-89.6, SHIV-KB9ecto, and SHIV-KB9 for the presence of syncytia. (C) COS-1 cells, transiently expressing the 89.6, KB9ct, KB9ecto, or KB9 envelope glycoproteins, were cocultivated with CEM×174 cells for 6 h at 37°C. The number of syncytia was scored and normalized to that observed for the parental 89.6 envelope glycoproteins. The mean values and SE derived from three independent experiments are shown.