Figure 5.
AA dependency of PG formation in the cell homogenates of P. falciparum. P. falciparum FCR3 strain was grown in medium with the addition of 33 μM AA for 48 h before harvesting. The parasite homogenates were incubated at 37°C for 30 min with various concentrations of AA added exogenously. The amounts of PGs produced were quantified as described under Materials and Methods. Triangles, circles, and squares represent PGD2, PGE2, and PGF2α, respectively.