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CD4+CD28null T cells do not associate with erosive disease. Frequency of CD4+CD28null T cells in paired samples of synovial fluid (left column) and peripheral blood (right column) from (a), (b) patients seronegative (ACPA-) and seropositive (ACPA+) for anti-citrullinated peptide/protein antibodies, and (c), (d) patients with or without erosive disease.
