Table 1.
Phenotypic Characterization of ERC
| Marker | Relevance | Expression |
| CD14 | Monocyte marker | Negative |
| CD34 | Hematopoietic stem cell marker | Negative |
| CD38 | Differentiating hematopoietic stem cell marker | Negative |
| CD45 | Pan-leukocyte marker | Negative |
| CD133 | Hematopoietic/angioblast marker | Negative |
| STRO-1 | MSC marker | Negative |
| SSEA-4 | Embryonic stem cell marker | Negative |
| Nanog | Embryonic stem cell marker | Negative |
| CD9 | MSC marker, associated with angiogenesis1 | Positive |
| CD29 | Adhesion molecule on mesenchymal and hepatic stem cells2 | Positive |
| CD59 | Complement inhibitor protein found on MSC3 and bone marrow side population CD34-stem cells4 | Positive |
| CD73 | Ecto-5'-nucleotidase, involved in migration of MSC | Positive |
| CD41a | Receptor for fibrinogen and vWF, found on MSC and platelets | Positive |
| CD44 | Hyaluronic acid receptor found on tissue stem cells and MSC | Positive |
| CD90 | Marker of T cells, hematopoietic and MSC | Positive |
| CD105 | Marker of tissue and MSC | Positive |
| hTERT | Telomerase reverse transcriptase | Positive |
| Oct-4 | Embryonic stem cell marker | Positive |
1 Kim YJ, Yu JM, Joo HJ, Kim HK, Cho HH, Bae YC, Jung JS. Role of CD9 in proliferation and proangiogenic action of human adipose-derived mesenchymal stem cells. Pflugers Arch. 2007 Aug 1.
2 Chiba T, Zheng YW, Kita K, Yokosuka O, Saisho H, Onodera M, Miyoshi H, Nakano M, Zen Y, Nakanuma Y, Nakauchi H, Iwama A, Taniguchi H. Enhanced Self-Renewal Capability in Hepatic Stem/Progenitor Cells Drives Cancer Initiation. Gastroenterology. 2007 Jun 20;
3 Izadpanah R, Joswig T, Tsien F, Dufour J, Kirijan JC, Bunnell BA. Characterization of multipotent mesenchymal stem cells from the bone marrow of rhesus macaques. Stem Cells Dev. 2005 Aug;14(4):440–51.
4 Preffer FI, Dombkowski D, Sykes M, Scadden D, Yang YG. Lineage-negative side-population (SP) cells with restricted hematopoietic capacity circulate in normal human adult blood: immunophenotypic and functional characterization. Stem Cells. 2002;20(5):417–27.