Table 2.
Protective effects of EPO and ERP on mice exposed to carboplatin
| Treatment | Carboplatin treated | Hematocrit (% change from basal)
|
|
|---|---|---|---|
| Mean | (SEM) | ||
| None (PBS control) | No | −6.8 | (2.2) |
| PBS | Yes | −42.5 | (7.3) |
| EPO | Yes | −27.9* | (4.2) |
| ERP | Yes | −22.3* | (4.1) |
Data are hematocrit values on day 8 as percent change from basal. n = 7–12 animals per group. ∗ = P < 0.05, compared with carboplatin-treated animals receiving only phosphate buffer injections. See Materials and Methods for details. Weight measurements indicated normal growth rate during this experiment.