Figure 2. NLX target is distinct from MOR but also bound by naltrexone.

A, Naltrexone but not morphine markedly reduced [³H]NLX binding in FLNA-expressing A7 membranes. n = 6. B, The absence of [³H]DAMGO binding using twice the amount of A7 membranes shows these lines do not express MOR. n = 4. C, Parent M2 melanoma cells do not express NLX targets. n = 4. * p<0.05 compared to control.