Figure 6. [³H]- and FITC-NLX binding to intact A7 cells is blocked by FLNA_2561-2565.

Intact A7 and M2 cells were incubated with 0.5 nM [³H]NLX or 10 nM FITC-NLX in the presence or absence of 10 nM VAKGL or VAAGL. [³H]NLX bound to A7 but not to M2 cells and VAKGL markedly reduced this binding to A7 cells (A). Likewise, FITC-NLX labelled A7 (B.I) but not M2 cells (B.II), and co-treatment with VAKGL (B.III) but not VAAGL (B.IV) abolished this FITC-NLX labelling in A7 cells (B). n = 4. * p<0.01 compared to vehicle.