Table I.

Serum Isoniazid and Rifampin Concentrations in Mice

	SKH1 mice			Humans
	Dose	Cmean	AUC	Dose	Cmean	AUC
	% diet	mg/L	mg · h/L	mg/kg	mg/L	mg · h/L
Isoniazid	0.02	0.77 ± 0.21	18.5 ± 5.0	5	5.4 ± 2.0a, 7.1 ± 1.9b	19.9 ± 6.1a, 48.2 ± 1.5b
Rifampin	0.05	3.09 ± 0.41	74.2 ± 9.8	10	14.91	117.93

^aRapid acetylators.

^bSlow acetylators.