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. 2005 Jan 3;201(1):19–25. doi: 10.1084/jem.20041836

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Copyright © 2005, The Rockefeller University Press

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Figure 4. — Serum cytokine productions by HZ and synthetic HZ (β-hematin) in vivo are dependent on MyD88 and TLR9. MyD88^−/−, TLR9^−/−, or wild-type (WT) mice were injected i.p. with either 1,500 μg of (a) purified P. falciparum HZ or (b) synthetic HZ (sHZ). Serum levels of MCP-1 and IL-6 were measured by ELISA at the indicated time points.