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. 2005 Jan 17;201(2):201–209. doi: 10.1084/jem.20041526

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Copyright © 2005, The Rockefeller University Press

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Figure 5. — Effect of a heterologous boost with MVA-PyCS. Groups of five mice were primed with different doses of 17D-Py and boosted i.v. 2 wk later with 10⁷ PFU of MVA-PyCS. All mice were challenged 2 wk later with 2 × 10⁴ sporozoites. Results are expressed as the mean ± SE of five mice per group. (A) Inhibition of development of parasite liver stages. (B) Number of IFNγ-secreting spleen cells after in vitro stimulation with the P. yoelii CS CD8⁺ T cell epitope.