Table 4.

Eleven classes of genomic elements subjected to evolutionary and population-genetics analyses.

Abbreviation	Description
CDS	Coding exons, as annotated by GENCODE
5′UTR	5′ Untranslated region, as annotated by GENCODE
3′ UTR	3′ Untranslated region, as annotated by GENCODE
Un.TxFrag	Unannotated region detected by RNA hybridisation to tiling array (i.e., unannotated TxFrag)
RxFrag	Region detected by RACE and analysis on tiling array
Pseudogene	Pseudogene identified by consensus pseudogene analysis
RFBR	Regulatory Factor Binding Region identified by ChIP-chip assay
RFBR-SeqSp	Regulatory Factor Binding Region identified only by ChIP-chip assays for factors with known sequence-specificity
DHS	DNaseI hypersensitive sites found in multiple tissues
FAIRE	Region of open chromatin identified by the FAIRE assay
TSS	Transcription start site
AR	Ancient repeat inserted early in the mammalian lineage and presumed to be neutrally evolving
CS	Constrained sequence identified by analysing multi-sequence alignments