Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2005 Mar 7;201(5):779–791. doi: 10.1084/jem.20041684

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2005, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 4. — Intratumor depletion of CD4⁺ cells leads to rejection of established tumor. 10⁵ Ag104L^d tumor cells were inoculated to C3B6F1 mice s.c. and 12.5–50 μg anti-CD4 antibody (GK1.5) was injected intratumorally, once every 7 d, starting 14 d after tumor challenge. The arrow indicated the first treatment. Spleen as well as tumor tissue were isolated from mice 2 d after CD4 depletion. The percentage of CD4⁺ T cells in the spleen or tumor tissue was determined by FACS (a). Tumor growth was monitored and data shown was representative pattern of tumor growth in one of five experiments comprising 21 mice (b).