Figure 5.

A Role for IL-2 in early development of CD4⁺CD25⁺ T_reg cells. B6 mice received either PBS (−) or α-IL2 mAb (+; 100 μg) on the day and 3 d after birth. 7 d after birth, lymph node cells from individual mice were subjected to FACS analysis. (A) The percent of CD4⁺CD25⁺ T cells. Data are mean ± SEM for 8–10 animals. (B) Dot plots of CD25 and GITR expression (left) and the absolute number of GITR⁺ cells for CD4⁺CD25⁺ cells (right). Data were mean ± SEM for three to four animals.