Table III.
HHV8 copy number in HHV8-infected patients
| Patient no. | Tissue | Diagnosis | Mean HHV8 copy no. ± SD (95% confidence interval) | IHC |
|---|---|---|---|---|
| (number/μg DNA) | ||||
| 23 | PBMC | CVID-control | 42.0 ± 20.6 (21.8–62.2) | NA |
| 10 | PBMCa | CVID-GLILD | 43.5 ± 16.5 (27.3–59.7) | NA |
| 11 | PBMCa | CVID-GLILD | 12.3 ± 8.7 (3.8–20.7) | NA |
| 16 | PBMC | CVID-GLILD | 16.8 ± 5.7 (11.2–22.3) | NA |
| 27 | PBMC | CVID-GLILD | 19.7 ± 9.2 (10.7–28.7) | NA |
| 29 | PBMCa | CVID-GLILD | 28.8 ± 12.7 (16.3–41.2) | NA |
| NA | lungb | HIV-1, +KS | 255 ± 141 (116–393) | + |
| 10 | small intestine | CVID-GLILD | 633 ± 501 (142–1,123) | − |
| 10 | colon | CVID-GLILD | 286 ± 117 (171–401) | − |
| 10 | bone marrow | CVID-GLILD | 414 ± 119 (297–531) | + |
| 10 | liver | CVID-GLILD | 375 ± 264 (117–634) | − |
| 10 | lung | CVID-GLILD | 405 ± 203 (206–604) | + |
| 11 | liver | CVID-GLILD | 434 ± 11 (423–445) | − |
| 11 | lung | CVID-GLILD | 17 ± 7 (10–24) | + |
| 11 | lymph node | CVID-GLILD (NHL) | 15,356 ± 1,100 (14,279–16,434) | + |
| 16 | lung | CVID-GLILD | 5 ± 3 (1.7–7.6) | − |
| 29 | lung | CVID-GLILD | 65 ± 41 (25–106) | − |
| 51 | lung | CVID-GLILD | 48 ± 22 (26–70) | − |
| 51 | lymph node | CVID-GLILD | 19 ± 12 (7–32) | − |
| 51 | liver | CVID-GLILD | 87 ± 73 (16–159) | − |
a
Patients with infection in PBMCs and tissues.
b
Kaposi's sarcoma (positive control).
NA, not applicable.